A .45 may not penetrate a vest, but the impact will knock somebody down.
The Clackamas shooter did not have a bulletproof vest, however. Some kind of cargo vest.
Head, neck, knee, arm, thigh; all fair game...and the groin. Don't forget the groin...and the rear end..hips, rear groin, quick incapacitation.
Clackamas mall shooter used stolen rifle; Wash. bill would change self-defense law
Authorities in Clackamas County say the rifle used by gunman Jacob Tyler Roberts was stolen earlier on the day of his rampage at a popular shopping mall from “a person known to the suspect.”
Oregon mall shooter used stolen rifle; Wash. bill would change self-defense law - Seattle gun rights | Examiner.com