Moved from 5 o'clock to 3 o'clock and...
I like it.
I'm a portly fellow so the 5 position was comfortable during standing, sitting, moving. Except when I sat down in a dining chair — my holster and gun would bump into the chair, making me uncomfortable.
But the 3 position isn't so bad. Actually, it's not bad at all. I use a N82 Tactical Professional (and S&W M&P9c), so the gun doesn't rub against my gut at all, which is great. And I can conceal it a bit better when wearing light clothing, like plain T-shirts.
Do you carry at different positions? If so, does it depend on what you're wearing? What you're carrying?