I choose to ride in two piece armored gear( crash armor not kevlar) every time I ride. My 1911 doesn't work IWB there, but in a shoulder rig it works great. Even with mesh panels it gets hot so i have to be wearing two shirts if I want to peel off the jacket without scaring the sheeple. Since I got my LCP it has become much easier. I don't really think the reduction in caliber is an issue, if I think i need to draw a weapon while riding the throttle is a far better response. The LCP can be fired from either hand if i really needed to. Last sunday coming home over the Sierras on Ebbetts's Pass I was in a major thunder storm with lots of hail as deep as two inches on the road. My gear has a rain liner that goes on the inside, so my LCP in the pants pocket got soaked, but a quick stripping and oiling at home was satisfactory, and plastic don't rust like an old .45.
I rode home from Colorado last month, 1150 miles in 16.5 hours. I had to stop at each state line to arm or disarm. Pain in the butt, 3 gun stops and 4 gas stops. The lightness of the LCP was like it wasn't even there. In CO and NV it wasn't.