I have a ClipDraw and used it for some time on a M1911. It's quite handy and unobtrusive on the firearm. I carried as usual - Condition 1 - IWB with no problems. The pants protect the trigger guard until the pistol is drawn. Drawing properly with the finger off the trigger is as safe as any other holster. There's no additional safety issue with the ClipDraw that doesn't exist w/other holsters if used properly. There's no substitute for practice and training. Mechanical safeties make a poor substitute.
I switched to a Milt Sparks VersaMax 2 because the ClipDraw only reliably supports uncanted carry and I was more comfortable with an FBI cant. Also, the VM2 provides leather between the slide and my body when I'm carrying under a t-shirt in hot weather, thus protecting the firearm from perspiration. Otherwise, I'd still be using the ClipDraw.