It's a handful, no doubt. On a light pistol, it really hits the hands hard, upon recoil. Assuming it works reliably in your gun, it's probably the best cartridge I can think of for a .45ACP. Very little smoke, blast is low though depends on the length of your barrel to match its stats, with enough recoil push and "snap" to grab your attention. Extremely smooth during cycling. I can't say much beyond range experience, as I have not taken it hunting or used it for other purposes.
Of all the cartridges I have used with 9mm and .45ACP, I can say that the DoubleTap flavors seem to be some of the smoothest and most reliable cartridges I have ever used. On a CZ P-01 9mm pistol, the 9mm JHP +P variant was utterly reliable, the best choice bar none. I wouldn't have any qualms using it in any .45ACP pistol in which I found it similarly reliable, assuming that the gun was heavy and long enough to handle the fair amount of "punch" this round has. In a 4" Wilson CQB where it's performing with flawless reliability, I would say it's probably the perfect choice. It would be mine.
About as close to a "12 gauge" as you're likely to get on a .45ACP pistol, 12 gauge.