I think there're two factors when figuring out how to include suppressors in my reasoning.
I want to balance the noise level with the effectiveness of the bullet. In a lot of ways, I expect that there's a direct trade-off between the two.
Another trade-off is between the mass of the bullet and the velocity of the bullet. So, assuming equal foot-pounds, is there a way to idealize round-choice for a suppressor? Do I want heavy bullet or a light bullet going through my suppressor? Is one quieter when it comes out? Is one more effective when it comes out? One main consideration is the speed-of-sound, I think, so I'm asking mainly despite that component.