There are some well publicized, so called analyses of shooting incidents being promoted, however, they are greatly flawed. Conclusions are reached based on samples so small that they are
meaningless. The author of one, for example, extols the virtues of his favorite cartridge because he has collected ten cases of one shot stops with it.
Probably more people in this country have been killed by .22 rimfires than all
other calibers combined, which, based on body count, would compel the use of .22’s for self-defense. The
more important question, which is sadly seldom asked, is what did the individual do when hit?
Physiologically, no caliber or bullet is certain to incapacitate any individual unless the brain is hit.
Psychologically, some individuals can be incapacitated by minor or small caliber wounds. Those
individuals who are stimulated by fear, adrenaline, drugs, alcohol, and/or sheer will and survival
determination may not be incapacitated even if mortally wounded.
Kinetic energy does not wound. Temporary cavity does not wound. The much discussed "shock"
of bullet impact is a fable and "knock down" power is a myth. The critical element is penetration. The
bullet must pass through the large, blood bearing organs and be of sufficient diameter to promote rapid
bleeding. Penetration less than 12 inches is too little, and, in the words of two of the participants in the
1987 Wound Ballistics Workshop, "too little penetration will get you killed."