I screwed up! loaded some 45 rounds and used the barrel of my Sig 250 to check the depth of the rounds (225 gr. lead flat point). Fell right in no problem.
Instead of removing the barrel on the Ruger p345, I just loaded the round to check. and the gun did not go fully in to battery (about 1/4" back), and locked up with a round in the chamber. Can't get the slide to move at all.