I have a 3.5" Snake Slayer. It will put all five 000 buckshot in a 10" circle at 15'. In a study titled "The Armed Citizen – A Five Year Analysis", the results showed that the average medium shots fired for home invasion was 2. Also, the range of most incidents was just in excess of touching distance. Most defenders made the shoot decision shortly before the criminal comes within arm's length. The vast majority of the invaders ended up on the losing end.
Two shots from my Snake Slayer lands ten 38sp sized projectiles in a 10" circle. Two shots from a standard handgun lands two projectiles. Now, I would never suggest that because of this the Snake Slayer is the best choice for everyone. But there is no doubt, in real life scenarios backed up by significant data, the .410 Bond would be a reasonable consideration. There is a very telling car jacking self defense post that tells of the demise of the carjacker due to the quick thinking and reaction of the driver. He used his Bond that he kept loaded with .410 buckshot.
A pair of 3" .410 buckshot is a scary thing. And it does go "BOOOOOOOOM"!
Not for everyone. There are lots of good choices out there.