I currently carry a Kimber Covert Carry (which is an Ultra Carry 3" with digital camo). It's a .45, so the recoil is certainly higher than with other guns that I own, but I don't notice it as being significant enough to diminish my accuracy at the range. My wife has also uses it, even during IDPA shoots and she LOVES it... She's small at 5'4" and 125 lbs.
I would agree with several of the statements indicating that "grip firmness" has a lot to do with misfires on a shorter barreled .45, although I would be foolish for not suggesting that it impacts any other gun and caliber similarly.
Rent a few different styles, models, and calibers. The .45 is a great choice, but perhaps not the right one for everyone. I have a multiple handguns, and love them all for different reasons and circumstances.