I'm sure there are many good short barrel 45's out there. Due to several poor performance issues it's my personal preference to stay with only full sized 45's similar in action style to the Colt that the 45 ACP was designed for. It's a great defense round but very susceptible to loading & ejection issues in the shorter action of short barrel pistols. Of course I'm 6-4 285# so carrying a larger pistol is a bit easier for me than it would be for a shorter smaller framed individual. The other advantage is more distance between the front and rear sites. Makes it easier and more accurate to shoot. Probably wouldn't matter in a real defense situation but make me feel more warm and fuzzy.