I think it to be impractical, as whatever you are blasting it with, plus any grit, needs to be able to run out, and then you need to get lube back inside and distributed. Seriously, the Centennial revolvers do not get much grit inside them. With all due respect, if you have to be asking these questions, it is probably best to have a 'smith or armorer do this cleaning for you. Once a year is the most that would be necessary, and unless the weapon is carried in a very dirty environment, less often would probably be OK. Most grit that gets into revolvers enters through the hammer slot, and Centennials do not have this.
If you really want to do this yourself, first of all, get screwdrivers specifically made to fit the S&W screws. This is VERY important. Remove the grip panels. Remove the sideplate screws. Keep the screws separate once they are out, as they are not the same. Open the cylinder, and remove the whole cylinder/crane assembly forward. Holding the weapon over a soft surface, right side down, gently tap the grip frame from below with a soft mallet. The sideplate should fall free. If it does not fall free, easily, then carefully reassemble, and let a pro do this job for you. When the sideplate does fall free, the hammer block safety will fall free also. Now, carefully "blast" the interior, then let it drain, and dry. Don't blast too forcefully, as some parts might be forced out of place, and perhaps across the room, never to be seen again. Apply a good lube; I prefer one that will dry, leaving a film of lube, such as EEZOX.
Now, hold the sideplate, interior side upward, and set the hammer block safety in place. You might need a diagram to do this, unless you already know how it all works. Note there is a tab at one edge of the sideplate, that must be tucked under the corresponding part of the frame first. Then proceed to gently press the sideplate into place. Notice I said "gently!" If gentle pressing does not work, wrap everything up, to protect the finish of the parts, and take it to a 'smith. Forcing anything can cause damage that will require an expensive, lengthy trip to the factory. Reassemble the cylinder, screws, and grips in reverse order. Sorry for the long post; if there is a way to make paragraphs, I have yet to learn how.