I don't have any firsthand experience with Glocks, I'm primarily a 1911 fan. I've considered picking one up from time to time though just for kicks - a Baby Glock in .45ACP or a 20/29 in 10mm. Overall I think they're good quality weapons and it mainly comes down to whether or not the grip profile and trigger pull feel "right" to you.
I do prefer a manual safety on my autos but Hell, my edc is one of two S&W revolvers so I guess it's not much different. :wink: