I have posted before my preferences so:
The safety issue is not really an issue as someone said if you are gripping the gun the safety is off. Only if you have small kids and make a habit of leaving your gun around will this come into play.
Glocks are great guns I personally do not like the grip and just something aesthetically unpleasing. While not important makes me move on.
M&P, another fine handgun but I would not carry due to the magazine disconnect. If for the range, absolutely. The mushy trigger is a $50 easy fix.
XD, my favorite in this price range especially for the grip. Customer service is as good as S&W which is as good as it gets.
1911s, I really love however since I came to handguns late in life, not growing up with a Colt in place of my baby rattle, the manual safety is an issue for me in a possible stress situatioin. I prefer a gunthat just goes bang.
My true preference in hot weather is a H&K P2000sk but that is about $200 above the others and not the best choice for everyone. When not carrying the P2000sk i use a SIG 226/220.