In later years I have decided to standarize (sortof). We have Glock G34's for our competition shooting, Glock G17 for HD, and Glock G26's for EDC. I have noticed that myself and particulary my wife have only one system and the familiarization really helps with our shooting and also really helps with my wife's confidence. She just wants to shoot and not have to worry about which system she has. I have found the Glocks to be the best for us because there are no external safeties or decocking levers to worry aobut. She use to have the Sig 232 which has the decocker and she had some issues with FTE so she never did have any confidence in the gun. We traded it for the G26 and she has never had an issue with it. It works every time for her.
I feel alot more confident that in the event my wife or my self ever need to defend our lives there will be no hesitation and concern about which gun we have.
By my signature you see that I do have a couple of other guns, but these are regulated to the safe and for fun shooting with the family, with the exception of the S&W 642 which I use when I can't carry the G26.