There is a self defense company here in ohio called TDI they have a 3 day course and they offer close combat training as well as alot of other training. they have designed a knife for LEO's that is available to civilians. I bought one the other day and I love it.
Here is a little background of the knife:
It was designed to be worn on your weak hand side. The design was to stop someone from taking your weapon off your hip. if they reach for your gun you are supposed to pull knife with weak hand, grab BG wrist and cut upwards from bottom to top of wrist, can also be used for throat in self defensive. They make 2 blades one straight, one seraded. I have enclosed a link to their site so you can check out the knife. I recommend the TDI classes in Ohio as well as the knife.
you can see the finger spot behind the blade that is where your "pinkie" finger should rest so when holding the knife if you swing like you are punching the blade should be on the bottom side of your hand to slash the neck,face,wrist.