I don't use Streamlight, but I have used the TLR1 in the past. I'm all for the new Surefire 500 lumen weaponlights, even for close quarters indoor work due to their powerful peripheral lighting. BUT, it does not appear that the TLR1 HP is designed the same way. With it's larger head, it appears to be designed for rifle use in areas where extended throw is needed. It seems the focused portion of the beam is considerably brighter than the TLR1, while the x300u's higher output is overall with peripheral lighting being key.
So, I'll take a Surefire x300u for rural, urban or CQB work. I'd take the TLR1 for the same use and the TLR1 HD for rural use where extended throw is needed but I don't think it would be my first choice compared to the standard TLR1 for home defense or searching structures.
Understand that my opinion is based on what I've read about the TLR1 HD and NOT personal experience like with the high output Surefires.