I've owned at least 2 dozen semi-auto's over the last 30+ years and ALL of them have had at least a couple of jams/FTE/FTF except for three. There is a fourth, my Taurus PT-945, that's been 100% reliable, but it's only had about 75 rounds at most shot through it (usually 20 or so at a time) in the year since I purchased it, so I don't feel comfortable saying too much about it's reliability just yet. Anyway, some guns have had a 1,000 or more rounds shot from them between FTF/FTE while others can't seem to fire off 50 shots without something happening. Still, when it comes to 100% reliability...
Ruger P-85 - got it NIB in the late 80's. After umpteen thousands of rounds, it's NEVER failed to work... period. I still have it and it's my bedroom gun.
Bersa Ultra Compact 9 - bought it NIB about 2 1/2 years ago. Fired about 1,500 rounds up to now with it and by far, it's the most comfortable and user friendly semi-auto I own. Come to think of it, it's about the user friendliest gun of ALL the three dozen or so handguns I currently have. It's what I used the last time I had to qualify at the range for my CC license.
SKYY CPX-1 - got it this past January. It's still new and only has about 250 rounds shot through it, but there have been no problems with the gun so far. Every time I've pulled the trigger it's gone BANG, and it's never had a FTE or a mechanical problem, so I can't complain.