You bet... took me a while, but I found a barely-used Single-Six at a gun show. Blued, 6-5/8" barrel, adjustable sights. I'd prefer the 5-1/2" barrel, but I don't carry it a lot so that's really not an issue, just a slight preference.
I do recommend the adjustable sight models, and if you live in an area where humidity is a problem, the stainless models are probably worth the extra cost for you. I'm in the Phoenix area, so blued works just fine for me.
The thing that took the longest for me to get used to was that the grip is a bit short and I have to tuck my pinky finger under the base of the grip. With the rimfire, there is zero problem because the gun balances well and the recoil is non-existent. The single-action trigger isn't light, but it is quite crisp with minimal overtravel.
My SS didn't come with a .22 Mag cylinder, but I located a spare from a gunsmith for cheap. Ruger wants then to be factory-fitted, but that's fundamentally to check the rotational indexing (timing). I checked mine with a home-made "range rod" and the timing seemed spot on, so I've popped off a few dozen magnum rounds. A lot more noise, for sure! Not so sure the bunny at 20 yards would know the difference, but it's always fun to have a choice.
I think a .22 revolver is a dandy training handgun for beginners, especially young ones, and the Single-Six at about 35 ounces is heavy enough to be steady in a 10 year-old's hands. Trigger management and safely de-cocking a loaded gun are easy to learn, and they instill good safety habits from the git-go. Loading no more than 6 rounds at a time also keeps 'em from the "bangbangbangbang did I hit anything?" syndrome, and allows more time to focus on hitting the target.
I shoot other .22 handguns more accurately, but not with any more fun than my Single-Six.