I love the idea of using a shotgun in a home defense situation. Accessibility is my issue. My EDC is with me 90% of the time. It is what I train with the most. And while I am sleeping it goes right by me. My shotgun is considerably larger and would not fit on my night stand. The shotgun lives in a safe to keep little fingers off of it and I don't leave my house without locking up all firearms.
I am sure there are super neato devices that can mount under my bed to lock the shotty up but aside from the little lady cramming tupperwares full of things under there; I would still then have to deal with some type of electronic device. I like my EDC to be my home defender due to accessibility, familiarity, and performance.