I started reloading so I could match loads to varmint rifles for accuracy. I reload everything I shoot out of a rifle. I have several rifles that have never had a factory round fired in them since I've owned them. My CZ527 American in .223 is my go-to ground hog rifle. I've killed several hundred of them with it shooting nothing but reloads optimized for minimum group size. No store sells ammo that shoots into tiny little groups like that does.
I reload for .17Remington, .223 Remington, .22-250 Remington, .243 Winchester, 7mm Rem Mag, and .30-06 Springfield in rifles, .380, .38Sp, 9mmP, .357 Mag, .45LC, .45ACP in handguns. I love every minute I spend doing it. Very relaxing, very gratifying.
Branched into handguns when I started loading ammo for my .45 LC Ruger BlackHawk. Moved to progressive press for semi-auto handgun ammo. I reload 9mmP for cost savings. Everything else is custom loaded for accuracy in the particular gun.