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Pros: Bigger boom than anything smaller, Debated about 10mm vs. .45 acp. Many rounds comparable to a .357 magnum. Some rounds are bordering .44 and .45. You can hunt with it. Ted Nugent owns a 10mm.
Cons: Ammo is a little harder to find and may be very expensive. I have found 10mm for less than .45. Not many platforms available in 10mm (I keep dreaming of a Sig 220 in 10mm, that would be hot.)
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The unreasonable person will determine what the reasonable compromise will be.
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