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As long as it's an altered physical state with some minor emotional consequences (for example being tired makes one irritable), I think you're okay. You may be slow or in pain and it may anger you more than usual that the tea the waiter brought is unsweetened but you're in your right mind.

If it's an intellectual or emotional state (for example clinical depression) with some physical consequences (depression makes people sleepy), lock it away. You're not in your right mind.
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