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IME:
The recommended size Meprolight will hit high at 7 yards, requires a 6 o'clock hold (I dislike) like the factory sights.
Meprolight low profile for a Glock 26/27 will hit lower, allowing me to aim on at 7 yards, preferred.
Truglo TFO (recommended size) hit pretty much on and my eyes pick them up quickly.
My personal preference is Truglo TFO with green front / yellow rear, I installed those on a 1911 too.
(Edit: yes, POI can be altered with bullet weight, 160 gr. Tac-XP hitting lowest, 185 up a bit, 230 gr. hitting highest)
 
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