I watched the "Lost" episode last night....
on tape after I got home from work, and was watching for the scene ExSoldier762 pointed out (I check out CombatCarry on my computer at work

).
They showed Sawyer's revolver several times throughout the show and it was always a standard open-to-the-left action, until he was sitting in the car getting ready to shoot the "bad guy". When he checked the cylinder, it clearly opened to the right.
My guess is this: that scene was probably filmed in Hawaii, where the series is actually located. Since he was supposed to be sitting in an Australian car, and Aussie cars have the steering wheel on the right side, they probably figured it was cheaper just to reverse the image on film than have a right-side-drive car imported for this brief scene.