I've been using HKS Speedloaders for some time now and I just recently got some Bianchi strips.
These are fantastic. Operation is intuitive, simple, and moron proof. They're easier to carry because they're flexible and flat.
The only caveat is that if you want to load 2 rounds NOW! emphasis on NOW! they are definitely just as fast as speedloaders if not faster. Now if you want to fill the cylinder, it's about the same with a nod to the speedloader.
But to load 2 rounds in 2 seconds or 6 rounds in 3 seconds... I'll go with the former for a real defense situation but it's still a consideration to make.
That is assuming I close the revolver on the right chamber... I hate hearing click when it should go boom. That's another consideration to make.